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Biotech / Medical : Pain Therapeutics, Inc. (PTIE)
PTIE 12.08-1.3%Jan 21 4:00 PM EST

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From: Jack@SI8/2/2006 11:01:22 AM
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Another pain drug from the PTIE/King alliance.

SOUTH SAN FRANCISCO, Calif. and BRISTOL, Tenn., Aug. 2 /PRNewswire-FirstCall/ -- Pain Therapeutics, Inc. (Nasdaq: PTIE) and King Pharmaceuticals, Inc. (NYSE: KG) announced today the initiation of a Phase I clinical trial to evaluate the effects of PTI-202 in humans. PTI-202 is a new drug candidate in the companies' collaboration to develop abuse-resistant opioid painkillers, a new category of drugs intended to prevent prescription drug abuse.

In November 2005, Pain Therapeutics and King Pharmaceuticals announced a broad strategic alliance to develop and commercialize four proprietary lead drug candidates. All four drug candidates are intended to be long-acting, abuse-resistant opioid painkillers. Two of these drug candidates are now in clinical testing:

Drug Name Description Clinical Status
Remoxy(TM) Abuse-resistant oxycodone Phase III
PTI-202 Abuse-resistant opioid (undisclosed) Phase I

PTI-202 is a long-acting opioid painkiller. Pain Therapeutics and King Pharmaceuticals have not yet disclosed the active pharmaceutical drug in PTI-202.

Pain Therapeutics recently submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) for PTI-202. FDA acceptance of this IND triggered the payment of a $5 million cash milestone from King Pharmaceuticals to Pain Therapeutics.

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