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Biotech / Medical : Ligand (LGND) Breakout!
LGND 200.290.0%Jan 8 3:59 PM EST

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To: Andrew H who wrote (13629)1/23/1998 1:00:00 AM
From: Henry Niman   of 32384
 
Andy, I think that the Premarin results, as well as the Drolxifene results, will really heat up the SERM race for osteoporsis and LGND will be in the thick of the battle. The PFE deal is really for osteoporosis as is AHP's TSE424. AHP will be even more anxious to get moving on TSE424 because Premarin is under fire, Evista goes on sale this month, and now PFE is focused on Droloxifene for osteoporosis (and I suspect that they are also planning on speeding up CP-366,156 dsevelopment - LGND has indicated that CP-366,156 is more efffective than Droloxifene). Moreover, the Droloxifene result may focus development of a rexinoid/Evista combo for breast cancer, which is part of the recent LLY deal.
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