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Biotech / Medical : Biotech Stock Picking for Charity - 2005

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To: Extra Pale who wrote (198)9/27/2005 11:25:57 AM
From: Icebrg  Read Replies (1) of 322
 
The company wrote:

A pooled analysis of XYOTAX treated patients from STELLAR 3, STELLAR 4 and the PGT202 trial demonstrated a statistically significant (p=0.004) survival advantage for women treated when compared to men

They were also referring to some data mining they had done on the Stellar 3 and 4, but who knows how many subgroups they had analysed before they come up with that advantage.

Clearly, FDA has not been impressed as they were not allowed to file on the subset without running a confirmatory trial.

There may very well be a survival advantage for men compared to women in this indication, but most probably that will apply to all the taxanes and not only to Xyotax. Which means that it will still be difficult to prove superiority compared to paclitaxel et. al.

Erik
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