Jeff, More information than you may have wanted on H Pylori.
H Pylori has been tied to cause of Ulcers. (The full name is Helicobator Pylori)
Here is info I copied from internet:
> I am wondering if anyone is doing research on where H. pylori can be the cause of Ulcerative Colitis. An article in Scientific American "The Bacteria behind Ulcers" stated: It seems reasonable, then, to suggest that persistent microbes may be involved in the etiology of other chronic inflammatory diseases of unknown origin, such as ulcerative colitis, Crohn's disease, ... I believe H. pylori are very likely the first in a class of slow-acting bacteria that may well account for a number of perplexing diseases that we are facing today.
>
> This was in the Feb, 1996 issue (pages 104-107) written by Martin J. Blaser M.D.
> The treatment for H. pylori is very simple and only takes two weeks. Has anyone with UC tried this treatment?
>
> thanks
> --------------------
> John Dey
> Las Vegas NV
John
>I have tried a course of antibiotics, specifically Cipro and Flagyl, It did not work for me but I am waiting to get strong enough to try a different antibiotic. I have an article called "On the use of Antibiotics in Crohn's Disease" J Clin Gastroenterol 1995.20(4) Raven Press. N.y.Kruiningem sugests that sometimes you need to experiment with different antibiotics. Go for it! you have nothing to loose all the other drugs Ie: Prednisone .I sometime feel the cure is as bad as the disease . Just think it took the doctor 16 years to convince the medical establishment the H Pylori was the cause of 95% of ulcers. I feel there is a connection between Crohns and bacteria. Please let me know if you try it how it works.
Good luck
Catherine
Here is some other info I found:
I am wondering if anyone is doing research on where H. pylori can be the cause of Ulcerative Colitis. An article in Scientific American "The Bacteria behind Ulcers" stated: It seems reasonable, then, to suggest that persistent microbes may be involved in the etiology of other chronic inflammatory diseases of unknown origin, such as ulcerative colitis, Crohn's disease, ... I believe H. pylori are very likely the first in a class of slow-acting bacteria that may well account for a number of perplexing diseases that we are facing today.
>>>>Here is abstract that might answer your question:
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Gastric ulcers~Gastric ulcers cured with antibiotics alone
A recent study showed that the use of antibiotics without concomitant acid suppression is sufficient to heal H. pylori-positive duodenal ulcers (see Journal Watch accession number 940315001 and Lancet 1994; 343:508-10.) According to this new randomized trial, the same is true for gastric ulcers. Eighty-five patients with H. pylori-positive gastric ulcer (not related to nonsteroidal anti-inflammatory drugs) received either four weeks of omeprazole or a one-week course of bismuth subcitrate plus tetracycline and metronidazole. At nine weeks, 95 percent of both groups had complete healing of ulcers. About half the patients were followed for one year. Recurrent ulcers were found in 12 of 23 omeprazole-treated patients and only 1 of 22 antibiotic- treated patients. When compared with antibiotic therapy, the only advantage of using omeprazole was more rapid pain relief during the first week of treatment.
Comment: Acid suppression appears to be unnecessary for promoting the healing of H. pylori-positive gastric ulcers; antibiotics alone are sufficient. This finding adds yet another link to the chain of evidence supporting a causal role for H. pylori in peptic ulcer. --AS Brett.
Citation: Sung JJY; et al. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Engl J Med 1995 Jan 19; 332:139-42.
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Well I think that covers your question they have some other things going on and I will see if I can dig up more on human genes in the works.
I wonder what the opportunities are in relationship to Ulcer treatment? Do you have any idea how much revenue is related to the H Pylori work? It sure seems that with todays society there are more and more ulcers everyday.
Tara |
