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Biotech / Medical : Novartis
NVS 123.79+1.0%Oct 31 9:30 AM EDT

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To: Grateful Reaper who wrote (254)12/4/1999 1:54:00 PM
From: gao seng  Read Replies (2) of 296
 
Yeah, probably won't be enough to move the stock in the near future. Best chart I can find is here: moneycentral.msn.com but requires you to download an activex control.

As for the cancer aspect, I think it is tremendously important. Key word is translocation. They may have found a methodology that could lead to many new drugs;

Chromosome Abnormalities and Cancer
There are a variety of types of chromosome aberrations that are associated with cancer and there are few generalities that can be made about these relationships. These various types of aberrations fall into two categories:

Acquired Chromosome Abnormalities
Constitutional Chromosome Abnormalities
Acquired chromosome abnormalities are found in most malignancies; they develop during the formation of cancer.

Characteristic of a specific type of tumor
For example... a translocation between chromosomes 9 and 22 [t(9;22] is found in chronic myelogenous leukemia (CML), resulting in a characteristic derivative chromosome #22 called the Philadelphia chromosome. A translocation between chromosomes 8 and 14 [t(8;14)(q24;q32)] is found in most cases of Burkitt's lymphoma.
Associated with differences in the malignancy of a cancer
For example... a translocation between chromosomes 9 and 22 [t(9;22)] is a sign of a poor prognosis in acute myelocytic leukemia (AML) whereas a translocation between chromosomes 8 and 21 [t(8;21)] is a positive sign.
Increased aberrations as malignancy advances
For example... acute myelocytic leukemia associated with a translocation between chromosomes 8 and 12 [t(8;12)] will tend to become more malignant as additional as additional chromosome aberrations appear, such as trisomy 8.
Neoplasms may have chromosome alterations that are:

characteristic of a specific tumor type
found in other types of tumors
unique to an individual patient.
A single meoplasm may exhibit different chromosomal abnormalities; i.e., the karyotype may vary from cell to cell although a given aberration may be traced back to a single cell.

Constitutional chromosome aberrations, found in each cell of the body, are sometimes associated with an increase in the presence of specific kinds of cancer. For example...

deletion of the q14.1 band on chromosome 13 is associated with retinoblastoma
trisomy 21, Down syndrome, has a 1% occurrence rate of leukemia
deletion of band p13 on chromosome 11 is frequently associated with childhood Wilms tumor of the kidney.

As an afterthought, the bio-agri business seems to be consolidating, and nvtsy is a big player in this field, which seems to be booming along quite well despite internet boycott groups, etc.

marketwatch.newsalert.com
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