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Biotech / Medical : TITAN PHARMACEUTICAL (TTP)

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From: John McCarthy12/12/2005 8:21:42 AM
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Titan Announces that Vanda Pharmaceuticals Initiates Phase III Clinical Trial of Iloperidone

SOUTH SAN FRANCISCO, Calif., Dec. 12 /PRNewswire-FirstCall/ -- Titan Pharmaceuticals, Inc. (Amex: TTP) today announced that Vanda Pharmaceuticals Inc. has initiated a Phase III clinical study of iloperidone, Titan's proprietary antipsychotic agent licensed to Vanda and in development for the treatment of schizophrenia and related disorders.

The study is designed as a randomized, double blind, controlled, three arm study. Patients in this
multi-center study will receive iloperidone, placebo, or an active control.

The study is designed to assess the efficacy, safety and tolerability of iloperidone in schizophrenic patients in acute exacerbation. The primary endpoint of the study is the reduction in the symptoms of schizophrenia as
assessed by the Positive and Negative Symptom Scale (PANSS).
Iloperidone is a novel 5HT2/D2 antagonist, antipsychotic agent in development for schizophrenia and other disorders.

prnewswire.com
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