There are lots of patents in the system, here are 2 more by Yingfu Li
2. WO/2024/059946MULTIVALENT TRIDENT APTAMERS FOR MOLECULAR RECOGNITION, METHODS OF MAKING AND USES THEREOF
WO - 28.03.2024
Int.Class C12N 15/115Appl.No PCT/CA2023/051253Applicant MCMASTER UNIVERSITYInventor LI, Yingfu
Multivalent trident aptamers comprising the general formula [A-SA]2 or 3-L-[SB-B] in which a central branched linker molecule (L) possesses 2 or 3 variable arms ([A-SA]2 or 3), and a root ([SB-B]), connected by a central carbon atom, to provide enhanced affinity and/or avidity with a target are described, as well as methods of making and using the multivalent trident aptamers are provided
3. WO/2024/059947HOMOTRIMERIC APTAMER FOR MOLECULAR RECOGNITION, METHODS OF MAKING AND USES THEREOF
WO - 28.03.2024
Int.Class C12N 15/115Appl.No PCT/CA2023/051255Applicant MCMASTER UNIVERSITYInventor LI, Yingfu
The present disclosure relates to molecular recognition elements (MREs) and, in particular, to aptamers for recognizing and binding to a microorganism, a virus, and/or a molecule present on a microorganism or virus, such as spike protein of severe acute respiratory syndrome coronavirus 2, and methods and uses thereof. |
