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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

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To: Mike McFarland who wrote (598)8/1/1999 2:56:00 AM
From: Mike McFarland   of 4474
 
A few fun quotes from PNAS pp. 8657-8662

"Peak hGH levels after each administration were
remarkably consistent, with no detectable
reduction between the first dose and the last
dose 10 months after viral injection"

That just takes my breath away.

"...AAV, as opposed to adenovirus or naked DNA,
does not efficiently transduce antigen-presenting
cells"

"...the system performed essentially identically
in immunocompetent mice as in immunodeficient
animals"

"Importantly, in the absence of rapamycin, protein
expression is undetectable" (I assume that is the
same as saying the system is not leaky)

Capn' Midnight, signing out.
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