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Biotech / Medical : Indications -- Stroke

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From: nigel bates2/22/2007 5:50:10 AM
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Ark wins key patent case on stroke in Europe

London, UK 22 February 2007 - Ark Therapeutics Group plc ('Ark' or the 'Company')
announces that following a hearing at the European Patent Office (EPO) it has
been informed by its patent attorneys, Gill Jennings & Every LLP, that it has
been successful in prosecuting Ark's patent application relating to its
intellectual property concerning the use of agents that affect the
angiotensin-renin system for the prevention and treatment of stroke.

The patent will cover 23 molecules belonging to the therapeutic classes of
angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor
(ATII) blockers, many of which are already marketed for various indications. The
geographic scope of the patent comprises the 18 European countries that belonged
to the European Patent Convention in 1998. The European patent will give
protection in the applicable European countries until 2018. Separate patent
applications are under prosecution in the USA as well as in other international
territories.

In April 2005, Ark signed a licence agreement with Boehringer Ingelheim granting
rights to Ark's intellectual property for the use of its products affecting the
renin-angiotensin system. The deal comprised upfront and milestone payments and
undisclosed royalties on sales of Boehringer Ingelheim's products for the
indication of stroke in all territories in which Ark has secured patent
protection. Formal grant of this European patent will trigger a milestone
payment from Boehringer Ingelheim to Ark. Further financial details have not
been disclosed.

Dr Nigel Parker, CEO of Ark, commented: 'We are very pleased to announce this
important patent news. The mitochondrial2 science on which the patent is based
was an exciting very early discovery by Ark scientists and we are pleased to see
the novelty being recognised by the European Patent Office in this third
therapeutic application. Ark will now start to consider the further commercial
licensing potential of the patent.'
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