CRIS, Curis (formerly CBMI) Message Board

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Biotech / Medical : CRIS, Curis (formerly CBMI)

CRIS 1.480

-0.7%

Oct 31 9:30 AM EDT

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To: Icebrg who wrote (663)	9/4/2009 7:31:46 PM
From: kkrramer	Read Replies (1) of 668

"This research opens the possibility of new anti-cancer therapies, specifically the use of RNA interference and of Cyclopamine, a plant product known to block Hedgehog pathway activity. This and other similar molecules can now be considered for future research as a treatment for terminal patients with metastatic disease and to fight resurgent forms of the disease." My understanding is that GDC-0449 is synthetic Cyclopamine. Does anybody know how proprietary and protected Curis/Genentech's formulation is? Ken

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