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Strategies & Market Trends : Contrarian Investing
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To: pcyhuang who wrote (687)11/6/2006 10:31:31 PM
From: pcyhuang   of 4080
 
NBIX -- Advancing Six New Drugs

Neurocrine is advancing six drug candidates through clinical development. The Company is expecting to report on several Phase II clinical trials in the fourth quarter of 2006 and throughout 2007. At the same time, Neurocrine scientists will continue to build Neurocrine's pipeline and meet the Company-wide goal of bringing one new compound into development each year.

GnRH Antagonists for endometriosis:
* Initiated a 6-month Phase IIb clinical trial with NBI-56418 for the treatment of endometriosis during the 4th Quarter 2006.
* Preliminary top line results from a second Phase II 3-month clinical trial in endometriosis evaluating additional dose response expected in the 4th Quarter of 2006.

Urocortin 2 for CHF:
* Results from a Phase II dose response trial involving patients with stable congestive heart failure (CHF) expected in the 4th Quarter 2006.

CRF Antagonists for IBS and Anxiety/Depression:
* Neurocrine expects the first exploratory studies in patients with irritable bowel syndrome (IBS) to start during the 4th Quarter of 2006.
* Neurocrine expects Phase II "proof of concept" trials in two indications, IBS and anxiety, to be initiated late in 2006.
* A back up compound is currently in Phase I multi-dose trials.

Selective Norepinephrine Reuptake Inhibitor (sNRI) for Neuropathic Pain
* New clinical candidate for neuropathic pain expected to enter Phase I clinical trials in late 4th Quarter 2006 or early 1st Quarter 2007.

pcyhuang
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