REDWOOD CITY, Calif., Feb. 9 /PRNewswire/ -- Anergen, Inc. (NASDAQ:ANRG) announced today that its collaboration with Novo Nordisk (NYSE:NVO) for AnergiX(TM) would be terminated, with all rights returning to Anergen. Novo Nordisk will reimburse Anergen for the cost of the ongoing multiple sclerosis Phase I clinical trial. The trial is expected to be completed in the third quarter of 1998. The Company also announced that it will be restructuring its workforce to meet anticipated future needs in research and development. "Novo Nordisk has previously publicly disclosed its move away from research and development in the central nervous system arena. Continuing the collaboration between the two parties did not seem to be in the best interests of either Anergen or Novo Nordisk," commented Barry Sherman, M.D., President and Chief Executive Officer of Anergen. "We continue to have a high regard for Anergen and its technology. Our decision is based solely on changes in Novo Nordisk's strategic direction and not any lack of confidence in the AnergiX technology," remarked Dr. Claus Kuhl, President of ZymoGenetics, Inc., Novo Nordisk's U.S. research affiliate. Under the terms of the agreement, all rights return to Anergen and the Company will not have any future obligations to Novo Nordisk. Therapeutic areas covered in the collaboration included multiple sclerosis, myasthenia gravis and Type I diabetes mellitus. "We view this as an important opportunity for Anergen to move forward in the development of our AnergiX products, and to find new corporate partners more closely aligned with our efforts in multiple sclerosis and other autoimmune diseases. We will conclude the Phase I trial in multiple sclerosis and, pending a favorable outcome, begin planning for Phase II trials," said Dr. Sherman. "Anergen will also restructure its operations to maintain our current burn rate, reducing our current workforce by approximately 15 persons. We are continuing our clinical development efforts with both AnergiX and AnervaX(TM), as well as emphasizing new research efforts for treating autoimmune disease." Anergen, Inc. is a biotechnology company focused on advancing the treatment of autoimmune diseases. It is developing proprietary biopharmaceutical compounds designed to selectively interrupt antigen presentation or inactivate T cells in the immune system that mediate the disease process. NOTE: Certain statements in this press release about the Company's utilization of resources, product development activities, clinical trials, and product pipelines, other than statements of historical fact, are forward looking statements, and are made pursuant to the Safe Harbor Provisions of the Private Securities Litigation Reform Act of 1995. Such statements involve risks and uncertainties. The Company's actual results could differ materially from the results discussed in these forward looking statements. Factors that could cause or contribute to such differences include dependence upon collaborative partners for the advancement of the company's research and development activities and future requirements for additional capital. These items are discussed in the Company's Form 10-K filed for fiscal year 1996 and the reports filed on Form 10-Q. SOURCE Anergen Inc. -0- 02/09/98 /CONTACT: David V. Smith, Vice President, Finance, and Chief Financial Officer, or Barry M. Sherman, M.D., President & Chief Executive Officer of Anergen, Inc., 650-361-8901; or media, Peter Steinerman of SBC, 516-374-3031, for Anergen, Inc.; or investors, Jonathan Fassberg of The Trout Group, 212-477-9007, ext. 16, for Anergen, Inc./ |