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Biotech / Medical : Indications -- Depression

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To: scaram(o)uche who started this subject8/9/2003 11:54:19 PM
From: scaram(o)uche   of 21
 
Message 19193794

Name / company Class Clinical trial status / attributes

elzasonan / Pfizer serotonin autoreceptor antagonist midstage / potentially faster-acting

CP 122,721 / Pfizer substance P antagonist late stage / may help those not responding to other antidepressants

aprepitant / Merck substance P antagonist late stage / may cause less sexual dysfunction

Cymbalta / Eli Lilly dual reuptake inhibitor completed / may be more potent than SSRIs

AR-A2 / AstraZeneca serotonin 1b antagonist early stage / novel class; may reduce anxiety

AZD-1134 / AstraZeneca serotonin 1b antagonist early stage / novel class; may reduce anxiety

GSK 352162 /
GlaxoSmithKline second-generation noradrenaline/
dopamine reuptake inhibitor early stage / may not cause any sexual dysfunction

GSK 679769; 597599/
GlaxoSmithKline neurokinin-1 antagonists early stage/ may reduce nausea and sexual dysfunction
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