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Biotech / Medical : Biotech Valuation
CRSP 56.27-0.7%3:59 PM EST
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To: tuck who wrote (10057)1/19/2004 10:44:26 PM
From: Biomaven   of 52153
 
tuck,

I think once the estimated number of genes dropped (if not before) it was pretty clear that the "one gene one protein" mantra was a serious over-simplification.

But from my limited knowledge I would doubt that this discovery will have much short or medium-term impact on drug development. Not only is it quite unclear how widespread this protein-splicing is, but I think there are more fundamental issues in genomics as a source of targets. I think the more significant factor is that cells are so complex and there is so much redundancy that most single genes are just not good targets in the first place.

Peter
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