This is a summary of what Merrill had to say about a month ago. I'll reproduce the full text if any one is interested
• Amending income statement model. Our estimates have been revised following Sanofi-Aventis’s (SNY, N) expansion of the oncology program, termination of the IL-1 Trap program in rheumatoid arthritis, and restructuring to conserve cash. • Restructuring to conserve cash. REGN's restructuring included staff reductions of 23%, and a projected year-end cash balance of $285-$295 mm. While management expects current cash balances to be sufficient until mid-2008, we have conservatively included an equity financing of $200mm in 2006E. • Neutral rating unchanged. Our income statement model only allocates modest placeholder revenues for VEGF Trap in oncology, due to lack of significant clinical data, and clinical/regulatory timelines. However, substantially higher upside potential exists pending appropriate data disclosure. In order to provide some context, we have provided a) Avastin’s approved and pending indications; b) ML estimates for Avastin revenues; and c) sensitivity analysis if VEGF Trap timelines were to be accelerated. We will review our investment rating pending further visibility on the development of VEGF Trap in oncology and AMD, IL-1 Trap in osteoarthritis and new niche indications, clarity on timelines to regulatory filing, and progress on the company’s management of cash reserves. |