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Biotech / Medical : Biotech Valuation
CRSP 53.54-3.1%Nov 18 3:59 PM EST

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To: Biomaven who wrote ()4/21/2000 1:53:00 AM
From: paradigm7241  Read Replies (1) of 52153
 
Amgen versus TKTX on Epo:

I would like to get everyone's opinion on the battle between TKT and Amgen with regard to the production of human Epo. Amgen is in litigation with TKT, arguing that TKT's production of native human Epo infringes on their patent whereby the production of human recombinant Epo in any vertebrate cell is protected. TKT forces the overexpression of endogenous human Epo by introducing a constitutively active promoter region upstream of the Epo gene in a human cell line which does not normally produce Epo. Amgen introduced an Epo transgene into CHO cells. No Epo transgene is used by TKT. I have set up a Transkaryotic Therapies (TKTX) thread to discuss TKTX and this issue. Please post your thoughts.
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