IDPH--Positive preliminary results for pivotal trial of ID Message Board

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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID

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To: I. Luttichuys who wrote (126)	11/21/1996 9:14:00 PM
From: Brad C. Dunlap	of 1762

Hi Bennett, and thanks for the info F.S. Wang. I have not recieved my copy as of yet which doesn't surprise me since I was warned that due to the large attendance they will get abstracts out as soon as possible but could not guarantee any time frames. I don't know why I was told by Idec the abstracts didn't have any detailed results when the C2B8/chemo trial was selected by the ASH for a podium presentation. If I'm not mistaken, podium presentations are usually for companies that have been hand picked for exciting results. How would they have selected C2B8/chemo for this presentation without the results? Maybe the individual was referring solely to the C2B8 trial as a stand alone therapy. The results look very similar to the data that was released on this clinic in March where 100% response rate was observed with a slightly higher complete response rate of 66% in the earlier trail. This is exciting data to see the similar reponse in the additional patients over the release made in March. It is going to be interesting to hear if there is a strong positive correlation with BCL-2 turning negative and duration of response since this is uncharted territory. I'll be sure to post any additional info on the abstracts and conference as it becomes available. Thanks again F.S. Wang this is important info. Oh by the way, Idec will be releasing the results of C2B8 as a stand alone therapy first[Sunday] followed by the C2B8/chemo on Monday the first week of December.. It was hinted that at Monday's presentation they were going to sneak the results of C2B8 as a stand alone therapy. I don't think they would consider this if the data was disappointing on C2B8 as a stand alone treatment.

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