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Biotech / Medical : Microcide Pharmaceuticals (MCDE)
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To: Pseudo Biologist who wrote (140)2/2/1998 8:11:00 AM
From: jackie   of 186
 
Pseudo,

I've often wondered if the use of bacteriophages against bacterial infections would be a viable option if we were to lose antibiotics.

There is a wonderful introduction and discussion of bacteriophages in the book entitled Viruses, part of the Scientific American series on various science topics. It discusses the early work of Felix d'Herelle and Frederick W. Twort. These two gentlemen are generally credited with the discovery of bacteriophages.

d'Herelle in particular pursued the idea of using phages in fighting disease and the idea was under intense study during the twenties and thirties. Of course the development of penicillin brought an end to the work. However, there were other problems. As the book points out, "bacteriophage therapy failed to show efficacy in curing diseases. The reasons for this failure remain unclear."

It would be interesting to see what approach these other groups you mentioned would have in dealing with these difficulties.

Regards,

Jack Simmons
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