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Pastimes : Heart Attacks, Cancer and strokes. Preventative approaches
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From: LindyBill10/21/2008 11:16:29 AM
   of 39288
 
"Salt Sensitive" Hypertensives

Background:
Perhaps salt is bad for everyone. Link to Vitamin D lost.
Many people think that salt increases blood pressure. Let us assume that is the case for hyper-responders. How can we determine who responses to salt? Salt-sensitive hypertensives? Are all individuals equally sensitive in the blood pressure to high salt intake? Is it true that Hypertension particularly the identification of subgroups of salt-sensitive individuals within the general population? How do you determine who is salt-sensitive or not salt-resistant subjects?
Idea:
Try low salt diet for 6 days and then try a high salt diet for 6 days and take blood pressure readings that same time of day.
How much salt to take?
In rats:
"high-potassium diets seems to have a protective effect against the development of vascular damage induced by salt loading mediated".

What is the percentage of people that response to salt?

Remarks?
Ideas?

Does this sound like a good idea?

Thanks. Dan F.

Dr. Davis

Hi, Dan--

Yes, a useful and practical experiment.

Speaking generally, in Caucasians with normal kidney and heart muscle (left ventricular) function, the effect is modest, perhaps a reduction in blood pressure of just a few mmHg. The African American population, however, is enormously sensitive with huge shifts in weight, fluid distribution, and BP. Some other races are intermediate.

But you can narrow the question down to an N=1 by conducting your simple experiment.

Let us know how it turns out.
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