Vion (formerly Oncorx) interesting play on Gene Therapy Message Board

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Biotech / Medical : Vion (formerly Oncorx) interesting play on Gene Therapy

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To: T L Comiskey who wrote (183)	3/2/2000 3:43:00 PM
From: T L Comiskey	of 370

Thursday March 2, 2:44 pm Eastern Time Vion says cancer drug Phase I test completed NEW HEAVEN, Conn., March 2 (Reuters) - Drug maker Vion Pharmaceuticals Inc. (NasdaqNM:VION - news) on Thursday said it has completed a Phase I study of a cancer treatment. The treatment, Triapine, works by blocking a critical step in the synthesis of DNA, preventing the replication of tumor cells. The Phase I study was designed to assess Triapine's safety profile and pharmacokinetics when administered intravenously as a two-hour infusion every four weeks. The study treated patients on nine dose levels of Triapine and they tolerated the treatment well, the company said, allowing further studies. Vion said it planned to continue enrolling patients into a second Phase I trial of Triapine administered daily for five days every four weeks. Other Phase I studies are planned, the company said.

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