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Biotech / Medical : Pharma News Only (pfe,mrk,wla, sgp, ahp, bmy, lly)
PFE 25.78+1.7%Dec 10 3:59 PM EST

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To: Sonki who wrote ()5/23/1998 10:40:00 PM
From: Sonki  Read Replies (1) of 1722
 
Big Pharma Report- 5/17/98 (from Big K)

-Big Pharma (+0.6%) tracked the Dow (+0.5% for the week)

-AHP (+8.0%), AMG (+4.3%) and SGP (+4.3%) were the weekly leaders, While PFE
(-6.0%), SBH (-2.8%) and PNU (-1.6%) were the laggards.

-SGP (+10.3%) is the clear May leader, while PFE (-6.0%) retreats from its highs.

-YTD PFE (+40.1%) now trails WLA (+51.5%) and SGP (+42.6%). These "Big Three"
have increased 46.1% YTD as compared to a 12% gain for "The Bottom 10).

Big Pharma Scoreboard- 5/15/98
Rankings
. . Price % Chg % Chg % Chg YTD
Rk Comp Ticker 5/15/98 Week May 1998 Week May 98 97
1 Warner WLA 188.19 1.2% -0.6% 51.5% 6 7 1 5
2 Scher SGP 88.56 4.3% 10.3% 42.6% 3 1 2 1
3 Pfizer PFE 104.44 -6.0% -8.2% 40.1% 13 13 3 3
4 Amer AHP 48.88 8.0% 5.0% 27.8% 1 2 4 10
5 Glaxo GLX 55.88 0.8% -1.2% 16.7% 8 8 5 7
6 Bristol BMY 110.12 1.1% 4.0% 16.4% 7 4 6 4
7 Pharma PNU 42.12 -1.6% 0.1% 15.0% 11 6 7 13
8 Amgen AMGN 61.69 4.3% 3.5% 14.0% 2 5 8 12
9 Abbott ABT 74.44 2.5% 4.7% 13.6% 4 3 9 11
10 Smith SBH 56.81 -2.8% -4.6% 10.4% 12 12 10 6
11 Merck MRK 116.75 -1.0% -3.1% 10.1% 9 11 11 8
12 J&J JNJ 70.38 -1.0% -1.6% 6.8% 10 9 12 9
13 Lilly LLY 68.44 2.1% -1.6% -1.7% 5 10 13 2
Big Pharma . 83.59 0.6% 0.0% 22.0% . .
Bottom 10 . 70.55 1.0% 0.4% 12.0% . .
Top 3 . 127.06 -0.2% -0.6% 46.1% . .
, . . . . . . . .
Dow Jones 9,096 0.5% 0.4% 15.0% . . .
S&P-500 1,109 0.1% -0.3% 14.2% . . .
NASDAQ 1,847 -0.9% -1.1% 17.6% . . .
30 Yr Bond 5.97% 0.00% 0.67% 0.00% .

Big Pharma News You Can Use

Click here for links to news, charts and quotes on Big Pharma.

Big Pharma
Yahoo Link
Motley Fool Link

ED News You Can Use

Click here for links to news, charts and quotes on ED stocks:

ED Stocks
Yahoo Link
Motley Fool Link

Special Report- Current PFE Performance and Predictions

On April 21, 1998, one day after reporting the first full week Viagra Rxs of 36,000, PFE
reached 121.75 before settling to close at 116 1/8. Volume for that day was 13.7 million,
a high for 1998. Since this all-time high, PFE has declined 14.2% to Friday's close of
104.44.

Why the decline in the face of great news and a steady general market? Here is a
special Big Pharma Report:

Profit-taking at Highs- As described by The Peabody Model, profit-taking at PFE highs
is basically a given. Since 1990, there have been 27 intermediate PFE highs (Peabody
Peaks) that have resulted in an average decline of 14.7% to intermediate PFE lows
(Peabody Valleys).

Viagra Specification- Viagra has been on the market for just over a month. During this
period, it has generated more Rxs than any other new product in pharmaceutical history.
In fact, according to an audit by a market research firm Scott-Levin, Viagra was the
13th most frequently prescribed pharmaceutical in April surpassing Norvasc and Lipitor.
Zithromax was #1.

Top 20 Brand-Name Pharmaceuticals Dispensed in April 1998

Brand Company New Prescriptions
1 Zithromax/Z-Pak PFE 1,610,000
2 Augmentin SKB 1,250,000
3 Claritin SGP 1,166,000
4 Premarin Tabs AHP 1,031,000
5 Synthrorid Knoll 933,000
6 Biaxin/Susp ABT 909,000
7 Cipro Bayer 909,000
8 Prozac LLY 873,000
9 Prilosec Astra Merck 848,000
10 Zoloft PFE 710,000
11 Paxil SKB 682,000
12 Amoxil SKB 592,000
13 Viagra PFE 570,000
14 Norvasc PFE 565,000
15 Lipitor WLA/PFE 562,000
16 Cefzil BMY 534,000
17 Lanoxin GLX 522,000
18 Ultram JNJ 516,000
19 Ambien MTC 495,000
20 Claritin-D-12 Hr SGP 471,000

As of May 1st, Viagra has an astounding 98% market share:

Viagra (+5 Weeks) Pre-Viagra Market Shares
. 5/01/98 % Change 3/27/98 % Change Mkt Sh Mkt Sh
. New Rxs Prior Week New Rxs 3/27/98 5/01/98 3/27/98
Viagra 269,842 +30% 0 ++ 98% 0%
MUSE 2,945 -16% 9,593 -69 1% 75%
Caverject 1,394 -11% 2,609 -47% 1% 20%

Total 274,181 78% 12,821 2,147%

New Rxs Refill Rxs Total Rxs
Viagra-5/01/98 269,842 16,429 286,271
Viagra- 4/24/98 207,868 7,508 215,376
Viagra- 4/17/98 113,134 2,109 115,243
Viagra- 4/10/98 36,263 429 36,692
Viagra- 4/03/98 546 0 546
Total 627,653 26,275 654,128

Viagra Unknowns- With this current unbelievable specification, what is the problem?

Simple, Viagra seems unbelievable to many analysts and even physicians. How can a
product be effective and safe in such a complex problem such as ED? They reason ...the
first month specification must be an illusion...just trial usage by men who have previously
injected themselves and placed pellets down their urethras. And besides...remember
Redux.. anything that is hyped and effective may be off the market in a few months.

Here are some examples of these ramblings and concerns that effected PFE last week:

Following the publication of the NEJM article and editorial, several analysts seemed
surprised that PFE will not be effective for all ED patients. One major analyst last week
even questioned whether Viagra will be effective in occasional ED since it has only been
studied in persistent ED.

Some physicians are seeking to "Redux" Viagra and make media headlines..

Curiously, Viagra's current efficacy and adverse reaction profile ...one month
post-launch...are exactly as published in the FDA approved labeling.

The Impact of Viagra- Analysts remain slow to revise their 1998 Viagra forecasts and
the corresponding effect on PFE. Just too early to commit..

Analysts' estimates of Viagra 1998 sales average only $500 million. At the current
specification rate, it is estimated that Viagra is selling at a rate of $80 million per month.
Accordingly, a very conservative 1998 Viagra sales forecast is $720 million.

Current Original
. 1998 Est 1998 Est
. (Billions) (Billions) Comments
Gruntal* $1.000 Peak annual sales of $4.5 B
Salomen Smith Barney* $0.655 $2.1 B (1999), $5.750 B (2002)
Merrill Lynch* $0.625 $0.350 $1.3 B(1999)
Bear Stearns* $0.600 $0.400 $1.2 B (1999)
PaineWebber $0.600 $0.600 $1.2 B (1999)
HKS & Co $0.500 $0.500 Estimate will be grossly revised
Nation Banc Montgomery$0.400 $0.400 $800m in 99,Up to $6B in peak
Standard & Poor's $0.400 $0.400 $3.0 billion by 2002
Hambrecht & Quist $0.345 $0.345 $.700 B (1999)
Deutsche Morgan $0.300 $0.300
Gerard Klauer $0.300 $0.300 $788 million in 1999
AG Edwards $0.225 $0.225 Reaching $1.0 B in 3-4 years
Schroder* ......................... $1.2 B (1999)
OrbiMed ........................ $1 B by 2002
ABN-AMBRO .......................... $1.8 B (2001)
Americal .........................$10 B over 5 years
Cowen ...........................$2.5B +(2001)
Goldman Sachs ----------------------------$1.5 B by 1999
Average $0.496 $0.382

Predictions

Expect Viagra specification to continue to grow until a leveling off in the summer.
Monday's report should be at the 300 M + level.The greatest impact of Viagra on PFE
will occur with a strong refill reports (reported every Monday) and actual sales data (due
July 17th).

However, you can expect continuing reports about Viagra's side effect profile of
headaches, flushing, and abnormal vision (3% of total patients). Given the nature of ED, I
believe that these side effects will have zero effect on Viagra's specification. Click here
to read an insightful article on this subject published in the LA Times.

Based on current specification trends and assuming no significant future significant
adverse reactions, Viagra will be the most successful first year launch in pharmaceutical
history. Viagra may actually break $1 billion for 9 month sales in 1998. Moreover, I
believe it will the #1 pharmaceutical product with sales over $3.5 billion by the year 2000.
This is substantially higher than current analysts' forecasts. The resulting incremental
profit
will propel PFE's R&D and future licensing agreements.

It may take weeks or months before analysts and "Da Street" agree with the above
statements. When this occurs, PFE will have a strong movement upward. As mentioned
earlier, I have revised my 1998 PFE high to 150.
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