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Biotech / Medical : Cytori Therapeutics, Inc.

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To: SnowShredder who wrote (199)11/17/2008 5:05:14 AM
From: SnowShredder   of 251
 
Composition of Matter Patent Allowance Covers Adipose-Derived Stem and Progenitor Cells

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Composition of Matter Patent Allowance Covers Adipose-Derived Stem and Progenitor Cells
Wednesday October 8, 7:30 am ET

SAN DIEGO--(BUSINESS WIRE)--A Notice of Allowance was issued to the University of California by the United States Patent & Trademark Office (“USPTO”) for composition of matter claims pending in a patent application licensed by Cytori Therapeutics (NASDAQ: CYTX - News). The allowed claims cover a population of stem cells, progenitor cells and other replicating cells, which can be obtained from human adipose tissue.

The allowed patent broadens Cytori’s current patent portfolio for adipose-derived cell therapies and strengthens Cytori’s ability to freely develop future therapeutics. The cells covered by the allowed claims are believed to encompass a clinically important subpopulation of cells within adipose tissue. The subpopulation of human cells described in the patent was defined by characterizing specific cell surface markers for cells, which posses the ability to self replicate and differentiate toward one or more lineages.

Specifically, the newly allowed claims are directed to cells expressing certain combinations of STRO-1+, CD29+, CD44+, CD71+, CD49D+, CD90+, CD105+, SH3, CD45-, CD31- and low or undetectable levels of CD106. Such cell surface marker studies are a robust method of describing stem and other cells. The University of California and the University of Pittsburgh jointly own the patent application containing these allowed claims.

The allowed patent application is distinct from the issued, allowed, and pending patents and patent applications related to Cytori’s Celution® System. The Celution System product platform is protected by a family of patents related to U.S. Patent No. 7,390,484 (“the ‘484 patent”) issued in June 2008. The ‘484 patent describes the Celution System technology which processes adipose-derived stem and regenerative cells at a patient’s bedside. U.S. Patent No. 7,429,488 covers Celution-based methods for cosmetic and reconstructive surgery applications. Allowed U.S. patents cover Cytori’s StemSource® Cell Banking platform and methods to create wide-ranging therapeutic formulations of the Celution output.

Cytori is building barriers-to-entry for its Celution based platform through a large intellectual property portfolio, proprietary know-how and trade secrets, as well as its business relationships.

About Cytori

Cytori’s (NASDAQ: CYTX - News) goal is to be the global leader in regenerative medicine. The company is dedicated to providing patients with new options for reconstructive surgery, developing treatments for cardiovascular disease, and banking patients’ adult stem and regenerative cells. The Celution® 800 System is being introduced in Europe into the reconstructive surgery market while the Celution® 900 System is commercialize globally for cryopreserving a patient's own stem and regenerative cells. Clinical trials are ongoing in cardiovascular disease and planned for spinal disc degeneration, gastrointestinal disorders, and other unmet medical needs.

Cautionary Statement Regarding Forward-Looking Statements

This press release includes forward-looking statements regarding events, trends and business prospects, which may affect our future operating results and financial position. Such statements are subject to risks and uncertainties that could cause our actual results and financial position to differ materially. Some of these risks and uncertainties include our history of operating losses, the need for further financing, regulatory uncertainties regarding the collection and results of, clinical data, dependence on third party performance, and other risks and uncertainties described under the "Risk Factors" in Cytori’s Securities and Exchange Commission Filings. We assume no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made.

Contact:
Cytori Therapeutics
Tom Baker, 858-875-5258
tbaker@cytoritx.com

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Source: Cytori Therapeutics
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