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Biotech / Medical : Lidak Pharm. [LDAKA]

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To: luis a. garcia who wrote (209)5/9/1997 9:16:00 PM
From: John Zwiener   of 1115
 
Hi Luis,
Looks good, cautiously. Off the bat, I'm not sure how patients how patients with Kaposi's would have done with no treatment. These lesions tend to come and go,,,and we don't know what other treatments these patients were taking. It's hard to draw relatively solid conclusions from this info, but it seems to be good

Why could this be a red hering? Well, were the patients just started on other anti-HIV drugs at the same time?, or were they already on treatment and had progessive Kaposi lesions? How do other patients that are in a similar situation do? I saw that the study had 28 patients, but only 10 were mentioned. What about the other 14. Were they placebo?, or were they dropped, and why?

It makes since that Lidakol would work since some believe that Kaposi"s is a tissue reaction to herpes virus and not really a true sarcoma (but there is also evidence that Kaposi's is a sarcoma also).
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