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Biotech / Medical : Coronavirus / COVID-19 Pandemic

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From: kidl

8/26/2022 8:52:44 AM

of 22867

Omicron boosters

"All adults should stay up to date with COVID-19 vaccination," the CDC has declared, after releasing a study that centers around coronavirus hospitalization this past spring. "Among hospitalized non-pregnant patients [from the end of March until the end of May], 39.1% had received a primary vaccination series and 1 booster or additional dose; 5.0% had received a primary series and =2 boosters or additional doses. In May 2022, the monthly population-based, 'age-adjusted' hospitalization rate among unvaccinated adults aged =18 years was 3.4 times as high (95% CI = 3.2–3.6) as rates among vaccinated adults who had received = 1 booster or additional dose."

Other findings: The total number of hospitalizations remained much lower than when the Delta variant was rampant last fall, when vaccinations were more effective at preventing hospitalization. Those over the age of 65 were hit the hardest, while those with two booster shots were less likely to be hospitalized than those with just one during the BA.2 period.

The data could hasten approval for Omicron-specific COVID-19 boosters. Pfizer ( PFE) and German partner BioNTech ( BNTX) submitted an application for FDA emergency use approval of the shots on Monday, while Moderna ( MRNA) followed suit on Tuesday. The New York Times this week also reported that the Biden administration is eying a campaign to begin the rollout of updated vaccines shortly after Labor Day.

Coming soon: FDA Commissioner Robert Califf said yesterday that the agency would not hold a vaccines advisory committee meeting on Moderna and Pfizer's new emergency use requests, as it feels "confident" in the extensive discussion that was held in June. "The Vaccines and Related Biological Products Advisory Committee voted overwhelmingly to include an Omicron component in COVID-19 boosters. FDA has no new questions that warrant committee input. Bivalent and multivalent vaccines are very common and modifying a vaccine to include different virus strains often does not require a change in other ingredients." ( 258 comments)

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