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Biotech / Medical : Oncothyreon

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To: scaram(o)uche who wrote (2173)5/23/2013 1:35:19 AM
From: biomachine56  Read Replies (1) of 2344
 
Looks like NVP is pursuing BKM120 in mCRC and SCCHN in combo with CTX.

What's your view on the early PX-866/CTX combo data? Seems very compelling for the N number wrt to response rates in CTX naive and, more importantly, pts with prior EGFR inhibitor therapy.

BKM120 and PX-866 don't look too different as monotherapy, except that BKM120 seems to have a wider range of toxicities, especially hyperglycemia and CNS effects.
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