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Biotech / Medical : Biotech Valuation
CRSP 57.58+0.9%3:59 PM EST
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To: Biomaven who wrote (23722)5/21/2007 6:50:37 PM
From: CrazyPete   of 52153
 
What you're saying is true (that statistical significance is a poor measure of practical importance), however, an odds ratio is a measure of effect size hence it is closer to being a measure of importance. I would not poo-poo an odds ratio of 1.64 for death due to MI. Especially since one might hope that a diabetes drug would reduce incidence of cardiovascular events.

That said, I'd rather see the long-term data that showed no evidence for increased risk, according to GSK. One wonders about the wording of their statement, since it would be consistent with their studies being under-powered. A stronger statement that they could have made, but didn't, would be that their long-term data was inconsistent with the reported increase in risk. But who knows if that was intentional.
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