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Biotech / Medical : Neurobiological Tech (NTII)

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Jan 2 9:30 AM EST

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To: Dr. John M. de Castro who wrote (261)	2/8/1998 6:59:00 PM
From: James Silverman	of 1494

John, A more pressing question for me is why no interest in memantine from big pharma or biotechs with related product lines (GILD/AGPH for example)? It has to say something that CNSI was able to license memantine for opthamalic uses to Allergan while NTII has been unable to license memantine for the seemingly far larger market opportunities. As memantine is an approved drug in Europe, for what indications is it approved for? What are its annual sales? How much off-label usage? Jim

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