Very nice sounding! Would be interested in hearing anything you find out.
"Preclinical findings demonstrating the ability of VP025 to significantly reduce key measures of inflammation and cell death in the brain and to improve physiological measurements that correlate with memory and learning activity were presented this past weekend at the 33rd Annual Meeting of the Society for Neuroscience in New Orleans, by Professor Marina Lynch, PhD, and her team from the Department of Physiology, Trinity College, Dublin, Ireland. The inflammation-induced loss of memory function, measured by the ability to sustain long-term potentiation, was significantly (p less than 0.001) reduced by VP025. This improvement was associated with significant (p less than 0.05) reductions in inflammatory markers in the hippocampus, the site of memory and learning in the brain, including the stress activated kinase c-Jun N-terminal kinase (JNK) and the pro-inflammatory cytokine interleukin 1- (IL-1 ). Furthermore, VP025 administration resulted in an increase in the hippocampal levels of the anti-inflammatory cytokine interleukin-4 (IL-4) (p less than 0.05) in this model." |
