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Biotech / Medical : VD's Model Portfolio & Discussion Thread

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To: scaram(o)uche who wrote (2730)10/7/1997 8:59:00 PM
From: Pseudo Biologist   of 9719
 
Rick, V1, the following article from the Journal of Immunology by BMY researchers seems to confirm the potential usefulness of anti-CD40L (cf. Biogen).

edoc.com

The title is "Long-Term Inhibition of Murine Lupus by Brief
Simultaneous Blockade of the B7/CD28 and
CD40/gp39 Costimulation Pathways"

Emphasis on long-term and brief blockade. I have to read it more carefully, but it does look as if you need to block both pathways in order to get full benefit.

PB
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