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Non-Tech : Bill Wexler's Dog Pound
REFR 1.554-4.1%Dec 8 3:59 PM EST

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To: gringodoc who wrote (2932)8/10/1999 11:06:00 AM
From: Marconi   of 10293
 
Hello GringoDoc: ZONA and proliferation of brown fat tissue in male rats

Hmmmm. Seems the potential issue resulted in a market reaction of Zona falling more than 2 points to near 5 $/sh. The fatuous comment from Zonagen's CEO Podolski,
"Phentolamine has been on the market for 50 years," said Joseph S. Podolski, President and Chief Executive Officer of Zonagen. "Given this and the fact that our previous trials showed no abnormalities, we believe we can provide sufficient information to the FDA to remove the clinical hold.
has no merit. He needs to clarify the statement so that prior male rat studies have shown no brown fat tissue proliferation as opposed to the implication nothing was seen in previous trials, suggesting that patients have been examined for fatty tissue proliferation and nothing has been found in parallel to the male rat indications. Or separately, that prior male rat studies do not support the latest indication. Such ambiguity is probably worth $2x11.2M shares, or $23M hit to market cap realized today. And rats, I have been hoping for a bouncein recent months to go short.

Rats! Rats! Rats!
I suppose that might be what Podolski is muttering too.
Best regards,
m
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