SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Personalized Medicine: Molecular Dx
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
To: sim1 who wrote (30)12/17/2009 4:50:37 PM
From: Steve Lokness   of 60
 
Stuart;

Wildly fascinating stuff! Thanks for posting.

"We can also see the desperate attempts of our genome to defend itself against the damage wreaked by the chemicals in cigarette smoke or the damage from ultraviolet radiation. Our cells fight back furiously to repair the damage, but frequently lose that fight."

The studies used powerful new DNA sequencing technologies to decode completely the genome of both tumour tissue and normal tissue from a lung cancer and a malignant melanoma patient. By comparing the genome sequence from the cancer to the genome from healthy tissue they could pick up the changes specific to the cancer

I always thought GeneLogic now the almost defunct Ore Pharmaceuticals should have done this - they had the cancer tissue bank and were into sequencing before losing their way. Lack of vision I think? Of course who would have thought it to be this hard in the beginning/

Research published in Nature shows that the genome of a lung cancer patient has more than 20,000 mutations: this total implies that a typical smoker would acquire one mutation for every 15 cigarettes smoked. The cancer genome is ravaged by mutations, many of which are repaired as the genome tries to defend itself.
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  

HomeMailHotSubjectMarksPeopleMarksKeepersSettings
Terms Of UseContact UsCopyright/IP PolicyPrivacy PolicyAbout UsFAQAdvertise on SI
© 2025 Knight Sac Media.  Data provided by Twelve Data, Alpha Vantage, and CityFALCON News