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Biotech / Medical : Paracelsian Inc (PRLN)

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To: Hank who wrote (3106)8/20/1997 4:46:00 PM
From: Rick Costantino   of 4342
 
Hank,

I not so sure it is the board that is tyring to get rid of Rhodes. Certainly Babish and Campbell would like to do so, along with most of the shareholders.

PRLN "goes unrecognized" because they have no Phase II data on their products. Typically, big pharm step in when they see a candidate with promising Phase II data, which tests for efficacy in a limited population. AndroVir just completed Phase I (and I'm not sure they even finished the trial, to be honest), and AndroCar hasn't even been filed to have the FDA approve Phase I trial. Phase I just tests that it is safe (although often one can get an idea of efficacy). The "compassionate use" data is only of limited value since it is not a rigorous, controlled test. Pre-clinical data is good for choosing candidates, but it is risky to gamble on getting to market. The odds get batter as the drug works its way though Phase I, II and III.

Question: Where did you see the posting in Finish (could you copy it here)?, and Does anyone know the language or someone who could translate for us?

Rick C.
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