In fact, maybe you ought to be increasing your testosterone - and I promise this is the last abstract for today:
>>>>>Brain Res 1999 Mar 13;821(2):383-91
Relations of hippocampal volume and dentate gyrus width to gonadal hormone levels in male and female meadow voles.
Galea LA, Perrot-Sinal TS, Kavaliers M, Ossenkopp KP
Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada. lgalea@psych.ubc.ca
The present study examined hippocampal volume and dentate gyrus width and their relations to gonadal hormone levels in adult male and female meadow voles, Microtus pennsylvanicus. Females were split into High and Low Estradiol groups based on the median estradiol level. Males were similarly split into High and Low Testosterone groups. Contrary to previous reports in wild meadow voles, there was no evidence of an overall sex difference in hippocampal volume. However, when male-female comparisons were limited to High Testosterone males and Low Estradiol females a significant sex difference in hippocampal volume favouring males did emerge. Hippocampal volume in males was related to testosterone level, with High Testosterone males having significantly larger hippocampi than Low Testosterone males. Similarly, there was a significant influence of plasma estradiol level on hippocampal volume and left dentate gyrus width, with High Estradiol females having larger hippocampi and dentate gyrus width than Low Estradiol females. In addition, consistent with previous findings in the laboratory rat, there were sex differences favouring males in right dentate gyrus width. These findings show that there is a complex relationship between hippocampal volume, dentate gyrus width and gonadal hormone levels in male and female meadow voles. Copyright 1999 Published by Elsevier Science B.V.
PMID: 10064825, UI: 99165641<<<<<
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