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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: Oliver & Co who wrote (3214)	12/8/1997 12:28:00 PM
From: Izzy	Read Replies (1) of 6136

Dr. Oliver: Thanks for the post. Pneumocystis carinii pneumonia (PCP) remains the most common pulmonary infection in HIV patients (more than 80% of AIDS patients will develop PCP and, in 60% of cases, PCP will be the presenting opportunistic infection). PCP usually presents as an acute pneumonia with the chest x-ray showing interstitial infiltrates in 75% of cases. However, other abnormalities include reticulonodular changes, air-space consolidation, solid/cavitary nodules, etc. Spontaneous pneumothorax can occur. Besides bronchoscopy with transbronchial biopsy, transbronchoscopic bronchoalveolar lavage (BAL) may confirm diagnosis. Fortunately, more effective treatment is now available and the prognosis has significantly improved. With improved antiretroviral therapy and more aggressive initial combo treatment, I would expect the incidence of PCP to decline.[I am a FCCP.]

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