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Biotech / Medical : NTEG- Bloodless Glucose Monitor
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To: Brander who wrote ()9/25/1997 10:26:00 PM
From: Stratajema   of 176
 
Brad. I think your experience in the field could be beneficial here. Are there any specific points that you care to address in my critique of TCPI's technology platform?

Since ISF glucose only has an approximate .95 correlation to capillary/venous glucose, the accuracy and consistency of the device and technology platform is extremely important. In very, very general terms (and I mean general!), a device with a measurement accuracy of 95% (Integ's goal and the current benchmark in SMBG devices), measuring ISF glucose that has a .95 correlation to blood glucose, gives an implied result that is 90% accurate (95% of .95).

I do not know of any way the TCPI measuring technology will provide the accuracy or the consistency to get even close to 85% accuracy.

I freely admit that TCPI's stock price will go up more from here. I am watching it closely and will short it when/if it gets into the stratosphere. TCPI is likely to reach the outer limits if they state they are filing for FDA approval. As a cautionary note, TCPI has not published any studies. If they pursue FDA approval without even giving a technical conference to investors then watch out. Even another competitor Cygnus(CYGN) also hasn't published any studies but they plan to conduct a technical conference for investors this fall to discuss their initial clinical results.

Also watch out for companies that mask their device accuracy problems by using the line "it's not accuracy that is key, it is frequency of testing". While the landmark diabetes study indicated the importance of frequency of testing, this does not make accuracy less important. The accuracy of the device becomes paramount when it comes time to inject a specific amount of insulin.
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