Thanks for the post. I also listened to the conference call.
While a promising step, there wasn't really any new inforamtion given out from the Aug 22dn press release. At least in specific scientific terms of c-mos kinase inhibition.
I am intrigued by their claim of an assay to differentiate patients infected with HIV that will develop AIDS rapidly vs. those with long-term chances for survival. To me, this is surprising and perhaps the MOST significant finding for PRLN to date. Not just important medically, but also in terms of commercial potential.
A few things I was not aware of...
(1) Results of Phase I PN355 will be by "end of year" (Nov,Dec 96?)
(2) Ongoing trials of PN355 will include adding other compounds (a combinatorial approach). These will include not only other compounds from the Chinese Traditional Medicine library, but also compounds which PRLN has synthesized. Dr. Babish said there were "7 to 12" candidates.
(3) In "9-15 months" PN355, or a cocktail including PN355 and other drug/s can be available as a "dietary suppliment". (Of course, in this case PRLN can not advertise that it can stop AIDS, as was not mentioned in the call.)
(4) PN355 is calso called Androvir...
Over all, things sounded very interesting and Dr. Babish certainly sounded excited. My only disappointment was that he did not mention (or did I miss it?) any "sceintific article" coming out. I eagerly look forward to reading this, as I was not satisfied by the level of scientific explanation in the call. Of course, this talk was not geared towards scientists, but analysts.
It will be interesting to see if this gets picked up by the media, an if there is any reaction to the stock. I really didn't see much happening yet...
Rick |