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Biotech / Medical : Paracelsian Inc (PRLN)

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To: Elllk who wrote (3418)12/8/1997 12:27:00 PM
From: Jonathan Schonsheck  Read Replies (1) of 4342
 
Dear Threaders,
As Bonnie croons, "Let's give them something to talk about . . .."

Paracelsian Completes Screening of Traditional Chinese Medicine Library

ITHACA, N.Y., Dec. 8 /PRNewswire/ -- Paracelsian, Inc. (Nasdaq: PRLN) announced today that it has completed the screening of its library of traditional Chinese medicinal (TCM) plant extracts. The Company used its battery of functional receptor and immunoassays to explore the biological activities of its entire library of 2,764 TCM extracts representing nearly 1000 plant species.

The Company's screening technology evaluates the effects of potential products on intracellular signals referred to as "Signal Transduction." Paracelsian scientists employed four core test systems to assay the entire TCM library for potential pharmaceutical products to address multiple disease targets. These assays included two biochemical targets, tyrosine kinase and the proprietary Ah-receptor, and two cell-based assays, proprietary CDK1 and HIV cell fusion. The latter assays evaluate the effects of potential products on whole cells and provide insight into the functional activities of test compounds.

"This is a significant body of work," said Thomas G. Tachovsky, Ph.D., President and CEO. "The Paracelsian scientists have identified functional activities among TCM extracts not seen before." The screening was performed to identify potential products for both the pharmaceutical and dietary supplement/herbal markets.

Paracelsian is seeking corporate partners among both classical pharmaceutical and dietary supplement companies to develop these herbal extracts. In addition, the Company will provide contract research for companies seeking to identify functional activities in their herbal products.

Paracelsian is a biopharmaceutical company engaged in the discovery and characterization of useful products from herbal sources. Its core technology consists of immuno- and cell-based signal transduction assays.

Copyright 1997, PR Newswire

CONTACT: Thomas G. Tachovsky, Ph.D., President and CEO of Paracelsian, 607-257-4224
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