Essential Therapeutics (ETRX) formerly Microcide (MCDE Message Board

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Biotech / Medical : Essential Therapeutics (ETRX) formerly Microcide (MCDE

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To: John O'Neill who started this subject	5/17/2001 7:37:49 PM
From: nigel bates	of 415

newscientist.com More than one in 10 British children are carrying superbugs resistant to one or more antibiotics. The proportion of adult carriers could be even higher... The finding has serious public-health implications, warns Michael Millar of Bart's and the Royal London School of Medicine, the study's author... The researchers were surprised by how many children were carrying bacteria resistant to antibiotics they had never been given... This implies that the genes that make the bacteria resistant are found on the same piece of bacterial DNA, and are passed on together. So giving people ampicillin can encourage bacteria to acquire and hang on to bits of DNA that make them resistant to other drugs as well... Doctors had thought reducing antibiotic use would curb resistance, because bacteria would lose resistance genes if they didn't need them. But this isn't happening. A recent study in The Lancet (vol 357, p 1325) showed that despite a 45-fold reduction in the use of sulphonamide antibiotics between 1991 and 1999, there was no reduction in the level of resistance. More at: The Journal of Antimicrobial Chemotherapy (vol 47, p 605)

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