fyi, the San Diego Union Tribune article ...
Agouron says sales of AIDS drug Viracept grow, reports a profit
By Thomas Kupper STAFF WRITER
January 13, 1998
Agouron Pharmaceuticals said yesterday that sales of its AIDS drug Viracept continue to grow, and the San Diego company reported its most profitable quarter yet.
It was a continuation of one of San Diego's first biotech success stories, which started last March when Viracept became the first local drug to win government approval.
In Agouron's second quarter, through Dec. 31, sales of Viracept reached $91.8 million, a 12 percent jump from the previous quarter. The drug became the top protease inhibitor as measured in revenue.
Analysts continue to revise their expectations of the drug upward, and Agouron said Viracept sales in the United States should hit $350 million for the fiscal year.
"They certainly can keep it up," analyst Elise Wang of PaineWebber in New York said. "There's no doubt in my mind."
Agouron reported quarterly net income of $4.9 million, or 15 cents a share, on total sales of $104.7 million including research contracts. A year ago, when Agouron had no products on the market, there was a $13.9 million loss.
Agouron shares closed yesterday at $30.25, down $1.93-3/4, before the announcement.
The largest share of AIDS patients on protease inhibitors continue to use Crixivan, from drug giant Merck & Co. that has about 40 percent of the market, compared with Agouron's 30 percent.
But Wang said that in terms of revenue, Agouron has about 36 percent of the market, because Viracept is more expensive than Crixivan. Agouron hopes to eventually overtake Merck in the number of patients.
The drugs are one component of the powerful AIDS cocktails that have dramatically improved the outlook for AIDS patients.
Despite the strong sales of Viracept, however, Agouron shares remain 45 percent below a September high. The company last month pulled the plug on its second drug project, the cancer treatment Thymitaq.
Analyst Charles Engleberg of AmeriCal Securities in San Francisco said that in the absence of new Agouron drugs -- which wouldn't come for several years -- or dramatic growth in Viracept sales, there isn't much to drive the stock up.
"The question is where are we going to get the upside surprises," Engleberg said. "On the other hand, we could see potential downside disappointment, just because there are new competitors coming into the market."
Those competitors include a new protease inhibitor from Massachusetts-based Vertex Pharmaceuticals that could hit the market this year as well as new variations on current drugs.
Additionally, some studies have suggested that patients eventually develop resistances to the protease inhibitors.
Wang said analysts are looking to presentations at upcoming medical conferences, including one next month, to get a better idea of how effective the Vertex drug is.
But she said Agouron could also have new data to strengthen its position, including studies of Viracept in combination with other protease inhibitors and in twice-a-day regimens, instead of the usual three doses. |