Alexion Pharmaceuticals, Inc. (ALXN) Message Board

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Biotech / Medical : Alexion Pharmaceuticals, Inc. (ALXN)

ALXN 182.50

0.0%

Jul 28 5:00 PM EST

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To: rkrw who wrote (383)	11/10/2003 4:07:57 PM
From: Ian@SI	of 824

After listening to the conference call, I still don't get it. The phase III indicates that there will be about 4000 fewer US deaths annually using Pex compared with not using it. Using the total population in the study, the results are significant. But it seems that because a pre-defined subset isn't significant (i.e. about a 1 in 15 chance of pure luck whereas the desirable level is less than 1 chance in 20.), thus another study will be required prior to seeking approval. Assuming a 2 year delay in approval, 8000 excess US deaths will have occurred - almost 3 September 11th tolls. Amazing.

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