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Biotech / Medical : Cell Therapeutics (CTIC)

CTIC 9.090

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Jun 26 5:00 PM EST

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To: Icebrg who wrote (413)	2/16/2005 9:07:30 PM
From: gcrispin	of 946

In a Mescape article summarizing the highlights of the Chemotherapy Foundation Symposium XXI, the following was noted by Dr. Burris: Looking at a summary of toxicities from a CT-2103 database, Dr. Burris noted that although the incidence of neutropenia appeared lower than that seen with similar doses of paclitaxel, this adverse effect is still clearly the dose-limiting factor for CT-2103 at doses greater than 235 mg/m2. Nine percent of patients on 175 mg/m2, 11% on 210 mg/m2, and 27% of patients on 235 mg/m2 have had grade 4 neutropenia. Cumulative neurotoxicity has also been observed, especially in patients who have received prior neurotoxic agents.

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