2012 Biotech Charity Contest Message Board

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Biotech / Medical : 2012 Biotech Charity Contest

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To: scaram(o)uche who wrote (428)	1/1/2013 10:54:45 PM
From: Biotech Jim	Read Replies (2) of 513

Rick- Thanks for starting this discussion. I have ZLCS in the charity contest and also own shares. Their N-type calcium channel blocker has a past history of being in the Neuromed-MRK collaboration prior to the Neuromed-CombinatoRx merger, and was given back to Neuromed by MRK due to poor po bioavailability in man. ZLCS has essentially closed down all of Neuromed (Terry Snutch company in Vancouver- Snutch being an expert on calcium channels -highly published in quality journals) so that expertise is gone unfortunately. This asset continues in the clinic for neuropathies as it has been formulated to increase po exposures substantially, ~ 6 fold. Should have a Ph2 readout soon. ZLCS needs to raise money, so my bet is they will do an offering after reporting positive Ph2 data for Z160. Jim

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