Review of the Year: Pharma M&A 
  shows its staying power    Published in  PharmaTimes magazine - December 2017                                                                                                                      by  Tom Cowap With macro drivers boosting the sector  and  a range of attractive themes driving interest, M&A in the  industry remains buoyant  Conditions have been ripe for M&A in the  pharmaceutical sector  in 2017. Low interest rates have provided cheap capital for both  financial and trade buyers, while acting as a disincentive to keep large  cash balances on reserve; the devaluation of the pound has heightened  the attractions of the UK for international investors; and economic  uncertainty has boosted the defensive pharma sector’s appeal.
  At a  global level, we’ve seen further blockbuster deals this year, led in  the contract research organisation (CRO) space. UK private equity firm  Pamplona paid $5 billion for Parexel; US CRO Covance acquired UK’s  Chiltern for $1.2 billion; PE houses GTCR and Carlyle combined to take  US CRO Albany Molecular Research private for more than $900 million; and  Inc Research and Inventiv merged in a deal worth $4.6 billion.
  In  the UK though, M&A has once again been led by mid-market  entrepreneurial businesses. Not only has international appetite for UK  businesses continued and private equity (PE) increased investment, but  we are also starting to see mid-market British businesses expanding  abroad via acquisition.
  One common theme has been interest in  businesses that specialise in niche, value-added services, putting them  in a strong position to benefit from big pharma’s search for new value  drivers and the rise of infrastructure-light biotechs. This is a  particular focus for PE, with deals such as Graphite Capital’s and  Phoenix Private Equity’s investments in Random 42 and Sygnature  Discovery respectively.
  Random 42 and Sygnature may deliver  different solutions but both provide value-added services to the  pharmaceutical industry in non-traditional niches where there is little  competition. Random 42 creates interactive experiences for the  pharmaceutical and biotech industry through animation and virtual  reality technologies, while Sygnature provides outsourced preclinical  drug development and research services. This service-led delivery model,  which relies less on ownership of a single drug or product, is highly  attractive to PE investors.
  The same principle, niche specialism,  is also driving trade deals. For example, Clinigen acquired Quantum  Pharma, who specialise in providing access to hard-to-get drugs,  supplying hospitals with medicines that are not licensed in one market  but are available elsewhere.
  Meanwhile, the trends that are  driving big pharma to outsource are creating opportunities for  mid-market businesses too. Take Quotient Clinical, which provides an  innovative CRO model it describes as “translational pharmaceutics”. The  firm’s differentiated outsourced drug development model has secured it  sufficient growth that it is now expanding overseas via acquisitions,  including in the US this year of QS Pharma for £60 million and Seaview  Research.
  The themes that make mid-market specialists so  attractive have also driven big pharma to diversify away from its core  model to look for improved returns, including into more brand-led  offerings. The leading Spanish generics manufacturer Laborotorios Cinfa  for example, acquired UK-headquartered Natural Sante, a food supplements  business.
  The pharma sector continues to undergo structural  change, creating opportunities for fast-moving, agile businesses. That  will drive further M&A activity and investment.
  Tom Cowap  is principal, specialist in the pharmaceutical sector at Catalyst  Corporate Finance. Look out for Catalysts’ Pharma Fast 50 in our March  issue, which will look at companies likely to be sources of future  M&A activity
  http://www.pharmatimes.com/magazine/2017/december_2017/review_of_the_year_pharma_m_and_a_shows_its_staying_power
 
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