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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ)

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To: BigKNY3 who wrote (4655)	1/16/1998 9:50:00 AM
From: Gene Voss	of 23519

BigKNY3: Your reference to the fact that many of these same investigators were involved with initial Muse studies proves my point. Study design and patient selection have everything to do with results. My suspicion is that when this product is released real patients will find it to be totally inadequate. Since placebos are effective in greater than 30% of patients in most studies Viagra will be perceived to be marginally effective. Still, the reality will fall far short of the hype. The PDE-5 inhibition is being touted as some mysterious Nobel prize winning discovery. This has served to legitimize the to date unsubstantiated clalims of success. P-N has waffled on his assessment of MUSE and published 69% efficacy in his studies, but verbally blasted the therapy as being only 10% effective this speaks volumes about his veracity and reliabilty. Depending on how the studies are designed virtually any result is possible with any agent. Believe it or not Pfizer, Vivus and all drug companies are after profits which only serves in many cases to get drug approval at any cost. Let's see the published studies for accuracy and design, followed by real world usage and see who dominates this market. GV

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