Anyone still holding??? NEW YORK--(BUSINESS WIRE)--Nov. 17, 1997-- Management Change and Key Findings on Drug Resistance Position Company for Advances
Innovir Laboratories, Inc. (Nasdaq SmallCap: INVR.O) - a company that has been developing technologies based on oligozymes (catalytically active oligomers) both for the treatment and prevention of diseases and also for genomic and pharmaceutical research - has announced its results for the third quarter ended September 30, 1997. For the third quarter ending September 30, 1997, operating expenses were $2.2 million, as compared to $0.6 million for the same period in 1996, due principally to the acquisition of Innovir's operations in New York in December 1996, and increased R&D spending in the European operations. The net loss for the third quarter of 1997 was $2.2 million, or $0.08 per share, versus a net loss of $0.6 million, or $0.06 per share, for the same period in 1996. Weighted average shares outstanding for the three months ended September 30, 1997, were 28.0 million versus 9.5 million for the comparable 1996 period. Operating expenses for the nine months ending September 30, 1997 were $7.3 million, as compared to $4.5 million for the same nine month period in 1996. The net loss for the nine months ended September 30, 1997, was $7.3 million, or $0.34 per share, compared to a net loss of $4.4 million, or $0.46 per share, for the same nine month period in 1996. Weighted average shares outstanding for the nine months ended September 30, 1997, were 21.4 million versus 9.5 million for the comparable 1996 period. Cash and short-term investments at September 30, 1997, were $1.8 million versus $6.4 million at December 31, 1996. Innovir's cash position at the end of the third quarter is sufficient to cover needs for the balance of 1997. Plans are being developed to cover cash needs during 1998, including the likelihood that majority shareholder VIMRX Pharmaceuticals will continue to provide funding. "With a new, expanded management team, Innovir is well positioned to sustain the development of oligozyme technology," said Thomas R. Sharpe, Ph.D., President and Chief Executive Officer. "Judging from recent research at Yale University, we are particularly excited about the potential that Innovir's EGS oligozymes may hold in overcoming bacterial resistance to antibiotics. We are also aggressively pursuing its development as a tool to aid target validation in drug discovery and for other therapeutic purposes."
Key Developments for the Year to Date On September 26, 1997, Dr. Sharpe was appointed to his current position at Innovir, succeeding Allan R. Goldberg, Ph.D., as Chief Executive Officer. Prior to this, Dr. Sharpe served as a consultant to VIMRX Pharmaceuticals Inc. He formerly served as President and Chief Executive Officer of OsteoArthritis Sciences, Inc., and also spent more than 25 years in research and development as well as management positions with The DuPont Company and The DuPont Merck Pharmaceutical Company. Also on September 26, David A. Jackson, Ph.D. - a member of Innovir's Board of Directors, as well as Executive Vice President and Chief Scientific Officer of VIMRX Pharmaceuticals - succeeded Dr. Goldberg as Innovir's Chairman. As the foundation for its ongoing research and development, Innovir has an exclusive worldwide license from Yale University to commercialize EGS oligozymes, which can prevent cells from producing excess protein, which causes many diseases. The technology is a direct outgrowth of the work for which Dr. Sidney Altman, Sterling Professor of Biology at Yale, was awarded the 1989 Nobel Prize in Chemistry. In August 1997, Dr. Altman and his colleagues announced that they have discovered a way to use Innovir's EGS oligozymes to make drug-resistant bacteria drug- sensitive by eliminating the bacteria's defenses. The findings are significant because an increasing number of diseases once thought to be under control - such as meningitis and tuberculosis - are developing resistance to antibiotics. Innovir Laboratories, Inc. (Nasdaq SmallCap: INVR.O) - a majority- owned subsidiary of VIMRX Pharmaceuticals Inc. (Nasdaq: VMRX.O) - is a biotechnology company that has been developing technologies based on catalytically interactive oligomers (oligozymes), for pharmaceutical and genomic research and also for the treatment and prevention of diseases. As a research aid, oligozymes hold potential both to identify how different genes function and to identify and validate molecular targets for new drug therapies. The Company's technologies utilize either External Guide Sequences (EGS) oligozymes - which inactivate targeted messenger RNA (mRNA) through use of cellular enzyme RNase P - or RILON(TM) oligozymes, which inactivate targeted mRNA directly. To complement its therapeutic and drug target validation programs, Innovir has developed a unique drug delivery tool called InnoPhor(TM) that makes it possible to target oligozymes to specific tissues. The Private Securities Litigation Reform Act of 1995 provides a "safe harbor" for certain forward-looking statements. The forward- looking statements contained in this release are subject to certain risks and uncertainties. Actual results could differ materially from current expectations. Among the factors which could affect the Company's actual results and could cause results to differ from those contained in the forward-looking statements contained herein are the success of the Company's clinical trials and the development of competing therapies and/or technologies by other companies. -0- NOTE TO INVESTORS AND EDITORS: Innovir's press releases are available on the Internet through VIMRX Pharmaceutical Inc.'s web site at www.vimrx.com and through BusinessWire's web site, under the VIMRX heading, at businesswire.com.the releases also are available at no charge through BusinessWire's fax-on-demand service at 800-411-8792. --30--rh/ny*
CONTACT: VIMRX Pharmaceuticals Media Contact: Laura A. Mastrangelo, 302/998-1734 or Investor Contact: The Investor Relations Group Dian Griesel, Ph.D., 212/664-8489
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