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Biotech / Medical : Human Genome Sciences, Inc. (HGSI)
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To: David Bogdanoff who wrote (60)2/27/1997 9:59:00 PM
From: Boyce Burge   of 1127
 
It seems to me the point is that genes are only patentable if you can describe their function. For about 200 or sogenes, HGSI can do that and they have filed patents. To avoid being outflanked, Merck has funded a group at Wash U to sequence ESTs and now this group has about as many partial gene sequences as HGSI...and they publish what they get immediately for all to ues!. This tends to erode HGSIs franchise and put them on an equal footing with other would be pharma companies. And its a long wait before one of their candidate drugs begins to show true clinical promise...though that will eventually happen. I think we will sit at 40 until there is information to relieve this bottleneck...maybe a decision by patent courts?

You might want to look at CEO Haseltine's article in this months Scientific American...he is upbeat and has some specific projections about what will be important in HGSIs future...he says that HGSI has concentrated its patenting on the G-protein-associated signaling molecules and that these should be among the most important disease related targets for drugs.

INCY also took a drubbing today, in part because of the fear that proprietary databases of genes may not be that crucial in drug discovery...but it was also overbought.
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