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Biotech / Medical : Mining Cholesterol
EVR 327.39+2.7%Dec 3 4:00 PM EST

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From: E. Charters6/3/2006 6:32:16 PM
   of 356
 
Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum.

ncbi.nlm.nih.gov

atvb.ahajournals.org

(Oxidized cholesterol comes from hydrogenated oils, meats, cheese, pasteurized milk. )

Fast Food, the "die" in diet

sciencedaily.com

"With the popularity of fried foods and the widespread fast-food industry, oxidized fats are common in the Western diet and could contribute to heart disease," says Ilona Staprans, Ph.D., of the Lipid Research Laboratory at the VA Medical Center in San Francisco.

Low-density lipoprotein (LDL) cholesterol is the "bad" form of cholesterol, but when it is oxidized, it can become even more dangerous. Oxidation occurs when cholesterol comes in contact with "free radicals," which are highly unstable, reactive oxygen molecules that circulate in the blood and damage tissues. Oxidized LDL cholesterol -- fat particles that have been combined with reactive oxygen -- plays a major role in the formation of artery-blocking plaque.

"Dietary oxidized cholesterol may contribute to atherogenesis, and dietary modification that reduces the intake of dietary oxidized cholesterol may have a role in the prevention and treatment of atherosclerosis," says Staprans.
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