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Biotech / Medical : PFE (Pfizer) How high will it go?
PFE 25.85+0.2%Dec 12 9:30 AM EST

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To: BigKNY3 who wrote (6330)11/23/1998 7:34:00 PM
From: Anthony Wong   of 9523
 
11/23 18:09 Merck<MRK.N> files osteoarthritis drug application

WEST POINT, Pa., Nov. 23 (Reuters) - Pharmaceutical Merck & Co. Inc.
said Monday it submitted a new drug application for Vioxx -- an investigational
once-daily, anti-inflammatory tablet for the treatment of osteoarthritis and pain
-- with the U.S. Food and Drug Administration.

The company said so-called COX-2 specific inhibitors are being studied to
determine whether the apparent difference in how they work may result in fewer
gastrointestinal side effects than nonsteroidal anti-inflammatory drugs.

Nonsteroidal anti-inflammatory drugs are drugs that are currently available for
the treatment of osteoarthritis and pain, it said.

The company said its application includes results from 68 studies in nearly
10,000 patients that evaluated Vioxx for the treatment of the signs and
symptoms of osteoarthritis and for the relief of pain.

Within 60 days, the FDA will determine whether or not it will accept Merck's
application as submitted, the company said.

Merck said it expects to begin to file similar regulatory applications for Vioxx
worldwide by the end of the year.

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