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Biotech / Medical : Depotech(depo)
DEPO 7.300+1.7%Aug 14 5:00 PM EST

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To: Sector Investor who wrote (650)12/22/1997 2:50:00 PM
From: Czechsinthemail   of 887
 
Michael King's comments on the side effects profile being skewed unfairly against DepoCyt were discussed by management during the conference call. They indicated that incidence of arachnoiditis were reduced by using steroids, but also that there may have been a reporting bias in noting virtually every detail on the experimental drug and possibly overlooking known side effects in the methotrexate group.
Hopefully, DEPO will be able to establish both the efficacy of DepoCyt through larger numbers and the ability of steroids to moderate the side effects profile. For now, I think the assumption of a higher toxicity profile for DepoCyt compared with methotrexate remains uncertain.
Baird
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