SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Ligand (LGND) Breakout!
LGND 181.04-2.7%1:07 PM EST
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
To: Harrison Hickman who wrote (7540)9/25/1997 6:35:00 AM
From: Henry Niman   of 32384
 
Harrison, I think that Robinson is calling for a legitamite re-evaluation. The ALRI contribution has always been a bit of a mystery because the pipeline was too big for an AGN/LGND joint venture, so even though there were many possiblities, it was hard to see how quickly they would be developed.

The new deal cuts LGND loose. They can do whatever they want with the products and still have AGN develop them (through deals with others) and get a royalty stream. Thus the products can be developed twice as fast and LGND's profits are higher (in the past everything except Targretin was 50/50 with AGN - now its mostly a 6% royalty rate - a bit higher for Panretin, but long term the first generation compounds (Panretin and Targretin) will be replaced with more specific and potent products anyway (ALRT1550 is more potent for cancer - "its better than we could have hoped for" and ALRT268 is more potent than Targretin - better results in mouse models of diabetes and stronger binding to RXRs).

I think that the diabetes deal with LGND will include a premium (or maybe it is tied to some post announcement time period to determine the price of the stock in the equity position - its all very hard to call because the deal will have several components - i.e. a royalty rate in addition to an equity rate and who knows what else (leptin?) will we included).
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  

HomeMailHotSubjectMarksPeopleMarksKeepersSettings
Terms Of UseContact UsCopyright/IP PolicyPrivacy PolicyAbout UsFAQAdvertise on SI
© 2026 Knight Sac Media.  Data provided by Twelve Data, Alpha Vantage, and CityFALCON News